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5 Best Alternative Pain Reliefs of 2025

Last Updated - 2025/08/28

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

ORVANCE

ORVANCE Orthodontic Wax, Clear Moisture Activated Braces Wax Alternative for Pain Relief, 72 Count

ORVANCE

CA$72.57

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Main highlights
- Works on all appliances including clear aligner trays.
- To apply, press and pinch adhesive side onto the wet appliance for 3-5 seconds to allow adhesive to set.
- Packaged in convenient single use applications – the standard for modern hygienic healthcare products.
- OrthoDots CLEAR are made of clear medical grade silicone with moisture activated adhesive technology.
- Now sticks even better – new adhesive is 2X stronger and even works on the edges of clear aligner trays.
CA$72.57
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

LivRelief

Livrelief Pain Relief Cream for Nerve Pain – Fast-Acting, Long-Lasting Relief with Natural Ingredients – Capsaicin Cream for Shingles, Sciatica Pain Relief & More – No Menthol, Paraben-Free, 50g (Pack of 2)

LivRelief

CA$38.49

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Main highlights
- Pack of 2
- LivRelief Nerve Pain Relief Cream provides fast and consistent relief from the agony of nerve pain and allows you to regain control over the life you wish to live.
- LivRelief Nerve Pain Relief Cream delivers the active ingredients quickly and consistently right where you need it.
CA$38.49
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

Medistik

CA$24.95

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Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, back pain relief, arthritis pain relief, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain relief and headache relief.
CA$24.95
4
Best Value
26% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Medistik
26% Off

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

Medistik

CA$33.20

CA$44.99
(26% Off)

More Details
Main highlights
- THE STRONGEST: MEDISTIK is by far, the strongest non-prescription topical pain reliever available, best alternative to Pain Relief Cream. Our long-lasting extra strength formula is ideal for serious pain management.
- RESTORE: Once applied, MEDISTIK promotes long-term healing by attacking inflammation in your body and providing lasting recovery and deep pain relief you can rely on.
- PRIME: Use MEDISTIK to prime and relax tight muscles for athletic training, peak performances, and day-to-day activities.
- PERFORM: When you’re in pain, use MEDISTIK to attack it directly. A powerful integrated system fights pain and inflammation at the source instead of masking it.
- ALL IN ONE SOLUTION: MEDISTIK works for tight muscles, chronic pain, pulled muscles, arthritis, joint pain, cramps and more. It also works for day-to-day irritations like sore feet, neck pain and headaches!
CA$33.20
CA$44.99 (26% Off)
5

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Independently Published

The Neuroscience of Chronic Pain Relief: The Best Alternative Chronic Pain Relief Solutions

Independently Published

CA$32.72

More Details
Main highlights
CA$32.72

5 Best Alternative Pain Reliefs of 2025

ORVANCE Orthodontic Wax, Clear Moisture Activated Braces Wax Alternative for Pain Relief, 72 Count

Livrelief Pain Relief Cream for Nerve Pain – Fast-Acting, Long-Lasting Relief with Natural Ingredients – Capsaicin Cream for Shingles, Sciatica Pain Relief & More – No Menthol, Paraben-Free, 50g (Pack of 2)

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis, Knee, Muscle & Joint Pain (1)

MEDISTIK Extra Strength Pain Relief Stick. Long Lasting Topical Pain Reliever for Backache, Arthritis Muscle & Joint Pain, 58g, Pack of 2

The Neuroscience of Chronic Pain Relief: The Best Alternative Chronic Pain Relief Solutions

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